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本文报道15年内BMRC协作组在香港,新加坡等地的临床研究结果。所用的药物为异烟肼(H)、链霉素(S)、利福平(R)、吡嗪酰胺(Z)、乙胺丁醇(E)和氨硫脲(T)。耐药性首先考虑H、S,其次为R(由于其它药之耐药性很少且资料不多,未作讨论)无论耐药与否均维持原方案。化疗期失败。失败指治疗结束前最后3个月内至少2次培养阴性。对耐药菌失败率:SH方案(20例)
This article reports the results of a clinical study of the BMRC collaborative group in Hong Kong, Singapore and elsewhere within 15 years. The drugs used were isoniazid (H), streptomycin (S), rifampin (R), pyrazinamide (Z), ethambutol (E) and thiosemicarbazide (T). Drug resistance first consider H, S, followed by R (due to other drugs with little resistance and little information, not discussed) regardless of resistance or not to maintain the original program. Chemotherapy failed. Failure means that at least 2 cultures were negative in the last 3 months prior to the end of treatment. The failure rate of drug-resistant bacteria: SH program (20 cases)