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Fouling deposition problem on heat transfer surface is widely distributed in the field of energy and chemical industry,and microbial fouling is a common fouling type in heat exchanger.In this article,the surface modification was used for inhibiting or mitigating the microbial fouling deposition on heat exchange surface.Firstly,the experimental system for real-time monitoring the fouling deposition process was built,and then the Ni-P modified surface was prepared.Further,the slime forming bacteria (SFB) microbial fouling characteristics and corresponding influencing factors on Ni-P modified surface were investigated experimentally.The results indicated that Ni-P modified surface had an excellent fouling inhibition property.Comparing with carbon steel,Ni-P modified surface reduced the fouling heat resistance by 80％.Accordingly,the influencing factors of microbial fouling deposition including temperature,flow rate and microbial concentrations were discussed.With cooling water temperature increasing given in the experiment arrangement,the microbial fouling resistance was increased first and then decreased,while with bacteria concentration and flow rate increasing,the fouling resistance was increased and decreased separately.The work can provide experimental reference for the fouling inhibition surface development and fouling inhibition mechanism study.