论文部分内容阅读
目的观察盐酸曲美他嗪(万爽力)治疗稳定型心绞痛的临床效果。方法将50例稳定型劳力型心绞痛患者随机分为两组。观察组25例,予口服万爽力20mg,3次/d、联合倍他乐克(美托洛克)、伯基(肠道阿司匹林)、长效的硝酸脂类、辛伐他汀等治疗;对照组25例,予口服倍他乐克、伯基、长效的硝酸脂类、辛伐他汀等治疗,12周为1个疗程。观察两组用药前后心绞痛发作情况、运动耐受改善情况、心功能及血压、心率、心电图的变化。结果观察组与对照组均能减少心绞痛发作,运动耐受及心电图均得到改善,但两组比较差异有统计学意义(P<0.05)。结论万爽力联合其他药物对稳定型心绞痛患者疗效显著。
Objective To observe the clinical effect of trimetazidine hydrochloride (万 爽力) in the treatment of stable angina pectoris. Methods Fifty patients with stable angina pectoris were randomly divided into two groups. In the observation group, 25 cases were treated with Wanqangli oral 20mg, 3 times / d, combined with metoprolol, bergamot (intestinal aspirin), long-acting nitric acid lipids and simvastatin. In the group of 25 cases, oral treatment with Betaloc, Burkina, long-acting nitrates, simvastatin and other treatment, 12 weeks for a course of treatment. The changes of angina pectoris, exercise tolerance, cardiac function, blood pressure, heart rate and electrocardiogram were observed before and after treatment. Results Both observation group and control group could reduce angina pectoris, exercise tolerance and ECG were improved, but the difference between the two groups was statistically significant (P <0.05). Conclusion Wanhuang force combined with other drugs in patients with stable angina significant effect.