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动物实验和临床实践提示,心得安有减少心肌缺血性损害的作用。本文通过动物实验,探讨在常温(37℃)和低温(27℃)下,心得安对心肌缺血的保护作用。方法:44个离体等容猫心用氧合的 Krebs-Ringers 重碳酸盐右旋糖酐(KRBD)溶液于主动脉根部作逆行连续灌注,窦房结压榨后用110次/分心房起搏。左心室内放入一乳胶囊,注入生理盐水以产生大约10毫米汞柱的左心室舒张期末期压,连
Animal experiments and clinical practice suggest that peace of mind has the effect of reducing myocardial ischemic damage. In this paper, animal experiments were conducted to investigate the protective effect of propranolol on myocardial ischemia at normal temperature (37 ℃) and low temperature (27 ℃). METHODS: Forty-four ex vivo isokinetic cardioversion Krebs-Ringers bicarbonate dextran (KRBD) solutions were perfused retrogradely in the aortic root, pacing the atrial node 110 times per minute with atrial pacing. Into the left ventricle, a latex capsule is infused with physiological saline to generate a left ventricular end diastolic pressure of about 10 mmHg, with