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目的通过毛细管电泳技术探讨妊娠期高血压疾病孕妇检测其血清蛋白的临床意义。方法采用法国Sebia全自动毛细管电泳仪,在孕晚期和孕中期对妊娠期高血压疾病孕妇组和正常孕妇对照组血清进行电泳,分析其电泳图谱。结果与正常孕妇组比较,孕晚期妊娠期高血压疾病组Alb和α1球蛋白差异有统计学意义(P<0.01),孕中期妊娠期高血压疾病组Alb和α1球蛋白差异有统计学意义(P<0.05)。结论血清蛋白毛细管电泳结果分析对妊娠期高血压疾病的早期发现具有一定的参考价值。
Objective To investigate the clinical significance of detecting serum protein in pregnant women with hypertensive disorder complicating pregnancy by capillary electrophoresis. Methods Sebia automatic capillary electrophoresis was used to detect the serum of pregnant women with gestational hypertension and normal pregnant women in the third trimester of pregnancy and the second trimester of pregnancy. The electrophoresis patterns were analyzed. Results Compared with the normal pregnant women, the Alb and α1 globulin in gestational hypertensive disorders in the third trimester of pregnancy were significantly different (P <0.01). The differences of Alb and α1 globulin in the third trimester of pregnancy-induced hypertension were statistically significant P <0.05). Conclusion The results of serum protein capillary electrophoresis have some reference value for the early detection of hypertensive disorders in pregnancy.