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目的探讨超声造影引导下微波消融联合经导管肝动脉化疗栓塞术(TACE)在治疗肝转移瘤的价值与疗效。方法转移性肝癌患者50例,单纯TACE组25例,微波消融联合TACE组25例,分析两组疗效。结果单纯TACE组CR 3例,PR 11例,SD 6例,PD 5例,缓解率为56%;TACE联合经皮微波凝固治疗(PMCT)联合组CR 7例,PR 15例,SD 2例,PD 1例,缓解率88%,两组缓解率比较差异有统计学意义(P<0.05)。联合组治疗后CD3、CD4、CD16CD56、CD3CD56水平明显高于治疗前(P<0.05)。结论超声引导下PMCT联合TACE治疗肝转移瘤能提高疗效。
Objective To investigate the value and curative effect of ultrasound-guided microwave ablation combined with transcatheter arterial chemoembolization (TACE) in the treatment of liver metastases. Methods Fifty patients with metastatic liver cancer, 25 patients with TACE alone, 25 patients with microwave ablation combined with TACE, and the curative effect of the two groups were analyzed. Results In the TACE alone group, there were 3 cases of CR, 11 cases of PR, 6 cases of SD and 5 cases of PD with a remission rate of 56%. TACE combined with percutaneous microwave coagulation therapy (PMCT) combined with CR 7 cases, PR 15 cases and SD 2 cases, PD in 1 case, the remission rate was 88%, the difference between the two groups was statistically significant (P <0.05). The levels of CD3, CD4, CD16CD56 and CD3CD56 in the combination group were significantly higher than those before treatment (P <0.05). Conclusion Ultrasound-guided PMCT combined with TACE in the treatment of liver metastases can improve the curative effect.