目的探讨胎儿不良结局与妊娠合并症及并发症之间的相关性。方法选取自2006年~2012年以来98例在我院分娩时产生的胎儿不良结局并且愿意接受做胎盘、脐带病理检查的妇女。通过研究其病史,得出发生不良结局的原因。与95例正常新生儿的脐带和胎盘病理检查结果(对照组)进行比较。结果接受脐带和胎盘病检的98例中,有病理改变占89例(90.8%),其中,发生绒毛纤维蛋白样坏死76例(77.6%),胎盘过大39例(39.8%),绒毛血管扩张45例(45.9%),胎盘形态异常25例(25.5%),脐带血管堵塞40例(40.8%),绒毛发育不良12例(12.2%);绒毛纤维蛋白样坏死率、绒毛血管扩张率、胎盘形态异常率、脐带血管堵塞率、绒毛发育不良率、胎盘过大率均远远高于对照组(P<0.05)。结论胎儿不良结局的产生主要是妊娠期胎盘和脐带出现病理变化,这与妊娠合并症和并发症关系密切,所以在妊娠期应特别注意各类并发症、合并症的发生,并及时做出解决,减少胎儿不良结局的概率。 Objective To explore the correlation between adverse fetal outcomes and pregnancy complications and complications. Methods From January 2006 to 2012, 98 cases of unintended fetal outcomes during delivery in our hospital were selected and women who were willing to undergo placenta and umbilical cord pathology were enrolled. By studying the history of the disease, the cause of the adverse outcome was obtained. The results of umbilical cord and placental pathology (control group) were compared with 95 normal newborns. Results Of the 98 cases who underwent umbilical cord and placental pathology examination, 89 cases (90.8%) had pathological changes, of which 76 cases (77.6%) had fibrinous necrosis, 39 cases (39.8%) had excessive placenta, 45 cases (45.9%) were dilated, 25 cases (25.5%) had placental abnormalities, 40 cases (40.8%) had umbilical cord occlusion, and 12 cases (12.2%) had villous dysplasia; fibrinous necrosis rate, villus vasodilation rate, The rate of placental abnormalities, umbilical cord occlusion, villus dysplasia and placenta were much higher than those in control group (P <0.05). Conclusion Fetal unfavorable outcome is mainly due to the pathological changes of placenta and umbilical cord during pregnancy, which is closely related to complications and complications of pregnancy. Therefore, special attention should be paid to the occurrence of complications and complications in pregnancy and timely resolution should be made , Reduce the probability of fetal adverse outcomes.