目的探讨双水平气道正压通气联合噻托溴铵吸入治疗老年慢性阻塞性肺疾病稳定期的临床效果。方法 90例老年慢性阻塞性肺疾病稳定期患者随机分为观察组(双水平气道正压通气联合噻托溴铵吸入治疗)与参考组(双水平气道正压通气),各45例,观察两组患者临床治疗效果、肺功能指标及患者生活质量。结果观察组治疗总有效率明显大于参考组,差异有统计学意义(P<0.05);观察组肺功能指标及生活质量改善情况明显优于参考组,差异有统计学意义(P<0.05)。结论双水平气道正压通气联合噻托溴铵吸入治疗老年慢性阻塞性肺疾病稳定期效果显著,有助于缓解症状,提高患者生活质量。 Objective To investigate the clinical effect of dual-level positive airway pressure ventilation combined with tiotropium bromide in the treatment of elderly patients with chronic obstructive pulmonary disease (COPD). Methods Ninety elderly patients with chronic obstructive pulmonary disease (COPD) were randomly divided into observation group (double-level positive airway pressure plus tiotropium inhalation) and reference group (double-level positive airway pressure) Clinical efficacy, pulmonary function and quality of life of the two groups were observed. Results The total effective rate of observation group was significantly higher than that of reference group, the difference was statistically significant (P <0.05). The improvement of pulmonary function and quality of life in observation group was significantly better than that of reference group (P <0.05). Conclusion Biphasic positive airway pressure ventilation combined with tiotropium bromide in the treatment of chronic obstructive pulmonary disease in the elderly has a significant effect of stabilizing period, which can help relieve the symptoms and improve the quality of life of patients.