作者报告一例63岁女性患者,诊断巴金森综合征。在中断大剂量抗巴金森综合征药物(每日服左旋多巴600mg、甲基多巴肼60mg、金刚胺600mg 和安克痉6mg)后大约一周发生罕见的复合症状,表现为锥体外系症状加剧、意识障碍、出汗、发热、血清肌酸磷酸激酶(CPK)增高至595单位,EEG 显示双侧θ活动过度,不时出现δ波。经过输液 The authors report a 63-year-old female patient diagnosed with Parkinson’s disease. Rare compound symptoms occur in approximately one week after discontinuation of high-dose anti-Parkinson’s disease medications (levodopa 600 mg daily, methyl-dopa hydrazine 60 mg, amantadine 600 mg, and ankasthin 6 mg), manifested as extrapyramidal symptoms Exacerbation, disturbance of consciousness, fever, fever, and serum creatine phosphokinase (CPK) increased to 595 units. EEG showed bilateral 活 hyperactivity and δ waves from time to time. After infusion