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目的:探讨乌拉地尔、硫酸镁治疗重度子前期的疗效。方法:158例重度子前期患者,随机分试验组与对照组各79例,两组均硫酸镁解痉,24小时总量20g,试验组5%葡萄糖500ml加乌拉地尔50mg静滴,根据血压调整滴数,24小时乌拉地尔总量≤100mg,对照组5%葡萄糖500ml加酚妥拉明20mg静脉滴注,根据血压调整滴数,24小时酚拉明总量≤100mg。结果:用药15分钟后试验组收缩压,舒张压均值下降分别为(14.69±10.69)mmHg和(12±8.57)mmHg,对照组收缩压,舒张压均值下降分别为(1.72±6.44)mmHg和(2.43±6.39)mmHg,两组差异有极显著性(P<0.01),脉搏胎心差异无显著性(P>0.05)。结论:乌拉地尔治疗重度子癎前期能快速控制血压,预防和控制子癎的发作,降低并发症,降低孕产妇及围生儿死亡率。间间
Objective: To investigate the efficacy of urapidil and magnesium sulfate in the treatment of severe preeclampsia. Methods: A total of 158 patients with severe preeclampsia were randomly divided into test group and control group, with 79 cases in each group. Both groups were given magnesium sulfate antispasmodic, the total amount of 20g in 24 hours, 500ml of 5% glucose and 50mg of urapidil in the test group, Adjust the number of drops, 24 hours urapidil total ≤ 100mg, control group, 500ml of glucose and 500ml of phentolamine 20mg intravenous infusion, adjust the number of drops according to blood pressure, 24 hours total phenylephrine ≤ 100mg. Results: The average systolic and diastolic blood pressure of the experimental group decreased by (14.69 ± 10.69) mmHg and (12 ± 8.57) mmHg respectively after 15 minutes of treatment. The systolic and diastolic blood pressure decreased by (1.72 ± 6.44) mmHg and 2.43 ± 6.39) mmHg, there was significant difference between the two groups (P <0.01). There was no significant difference in pulse fetal heart rate between two groups (P> 0.05). Conclusion: Urapidil can reduce blood pressure in preeclampsia, prevent and control the incidence of subfamily, reduce complications and reduce maternal and perinatal mortality. Between rooms