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目的:分析真菌医院感染的诊治情况,评价真菌鉴定、药敏分析在治疗中的价值。方法:分析2014年1月~2016年12月,各个年份的真菌感染情况。结果 :2014、2015、2016年真菌感染率差异无统计学意义(P>0.05),三年整体住院真菌感染率0.25%;真菌感染占同期感染的18.00%(303/1683),主要为白色念珠菌、光滑念珠菌、热带念珠菌,感染的部位主要为下呼吸道感染、泌尿道感染、尿管相关泌尿系统感染、菌血症。72h后,显效51.49%,有效37.62%,无效或加重10.89%。显效者初次用药为敏感药物率高于其他患者,差异有统计学意义(P<0.05)。结论 :真菌诱发的院内感染率较稳定,菌种较集中,但仍需要做好感染的数据统计、药敏分析,指导经验性用药,提高初次用药的敏感性。
Objective: To analyze the diagnosis and treatment of fungal nosocomial infections and evaluate the value of fungal identification and drug susceptibility analysis in the treatment. Methods: Analysis of fungal infections in various years from January 2014 to December 2016. Results: The prevalence of fungal infection in 2014, 2015 and 2016 was not significantly different (P> 0.05). The overall hospital infection rate was 0.25% in three years. The fungal infection accounted for 18.00% (303/1683) of the same period of infection, mainly white rosary Candida, Candida glabrata, Candida tropicalis, the main infection of the lower respiratory tract infection, urinary tract infections, urinary tract-related urinary tract infections, bacteremia. After 72h, 51.49% effective, effective 37.62%, invalid or worse 10.89%. The effective rate of initial drug use was higher than that of other patients, the difference was statistically significant (P <0.05). CONCLUSIONS: Fungal-induced nosocomial infections are more stable and the bacterial species are more concentrated. However, statistics on the infections, drug susceptibility analysis, and empirical medication are needed to improve the sensitivity of initial drug use.