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抗生素拯救了许多病人的生命 ,而细菌在与抗生素接触的过程中总是很快地学会了与新的抗生素相对抗的办法。目前的研究成果表明 ,细菌以 4种方法使抗生素失活 :(1)产生各种灭活酶 ,如 β -内酰胺酶、氨基糖苷钝化酶等 ;(2 )作用靶位改变 ;(3)改变细菌膜对抗菌药物的渗透性 ;(4 )
Antibiotics save the lives of many patients, and bacteria always quickly learn to counter new antibiotics in their exposure to antibiotics. The current research results show that the bacteria inactivate antibiotics in four ways: (1) producing various inactivated enzymes such as β - lactamase and aminoglycoside inactivating enzymes; (2) the target of action is changed; and (3) ) To change the bacterial membrane permeability of antibacterial drugs; (4)