溃疡性结肠炎(ulcerative colitis,UC)是一种主要累及直肠、结肠黏膜的慢性非特异性炎症,以腹痛、腹泻、黏液血便、里急后重为主要临床表现[1];病程迁延不愈,长达十几年甚至几十年,亦有发生癌变的可能性[2]。流行病学资料提示,UC的发病率不论在国内和国外都有逐年增高的趋势[3, Ulcerative colitis (UC) is a chronic non-specific inflammation mainly involving the rectum and colonic mucosa. Its main clinical manifestations are abdominal pain, diarrhea, bloody mucus and tenesmus [1]. The course of disease is prolonged by up to ten A few years or even decades, there are also the possibility of cancer [2]. Epidemiological data suggest that the incidence of UC, both in the domestic and foreign countries have increased year by year trend [3,