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为探讨极低出生体重儿（VLBW）外用静脉导入中心静脉导管（PCVC）与细菌感染的相关性,对43倒置入中心静脉导管的VLBW和75例经外周静脉穿刺的VLBW,进行回顾性分析。结果显示:8例VLBW发生1次或1次以上细菌感染,感染率为18.6％（8/43）。其中,6例感染病例成功治疗后保留导管,2例治疗后无效拔管。对相关细菌感染的高危因素进行综合分析,并应用Logistic回归分析法得出PCVC应用不是细菌感染的独立高危因素（比值比和95％可信区间分别为0.5,0.21～2.72）,机械通气时间和静脉输脂肪乳时间（比值比和95％见可信区间分别为2.2,1.43～7.96和4.7,2.98～9.86）为细菌感染独立高危因素。因此,认为PCVC作为长期提供静脉营养的基本途径,可以在感染的VLBW继续保留导管,延长PCVC的使用时间。
To investigate the correlation between PCVV and bacterial infection in VLBW patients, we retrospectively analyzed VLBW of 43 inverted central venous catheters and 75 peripheral venous punctured VLBWs. The results showed that eight cases of VLBW occurred one or more bacterial infections, the infection rate was 18.6% (8/43). Among them, 6 cases were successfully treated catheter infection, 2 cases of extubation after treatment. The risk factors related to bacterial infection were analyzed comprehensively, and the application of Logistic regression analysis showed that PCVC was not an independent risk factor for bacterial infection (odds ratio and 95% confidence interval were 0.5,0.21 ~ 2.72, respectively), mechanical ventilation time and Intravenous fat-transfer time (odds ratio and 95% confidence interval were 2.2, 1.43 to 7.96 and 4.7, 2.98 to 9.86, respectively) were independent risk factors for bacterial infection. Therefore, PCVC is considered as a basic way to provide parenteral nutrition for a long period of time, catheters can be kept in the infected VLBW, prolonging the use time of PCVC.