论文部分内容阅读
运用流式细胞仪（ＦＣＭ）和免疫组化技术对５５例睾丸肿瘤ＤＮＡ倍体和ＨＬＡ－Ｉ抗原表达进行分析。３例二倍体肿瘤均存活，异倍体肿瘤中非三倍体肿瘤３４例，死亡７例，平均存活时间４１．２个月，三倍体肿瘤１６例，死亡１０例，平均存活时间１５．５个月（Ｐ＜０．０５），ＨＬＡＩ－抗原阳性者２７例，死亡４例，平均存活４０．０个月，阴性者２５例，死亡１３例，平均存活１２．７个月（Ｐ＜０．０５），综合二者进行评估时，ＨＬＡ－Ｉ抗原阴性的三倍体肿瘤预后最差（Ｐ＝０．００１）。提示多参数综合分析在肿瘤预后预测中有十分重要的实用价值。
The DNA ploidy and HLA-I antigen expression in 55 cases of testicular tumors were analyzed by flow cytometry (FCM) and immunohistochemistry. All three diploid tumors survived. Tumor aneuploid tumors were non-triploid in 34, with 7 deaths, with an average survival of 41.2 months, 16 triploid tumors, 10 deaths and a mean survival time of 15 .5 months (P <0.05). There were 27 cases with HLAI-antigen positive and 4 cases died with an average survival of 40.0 months, 25 cases were negative and 13 cases died, with an average survival of 12.7 months (P <0.05). When evaluated in combination, HLA-I antigen-negative triploid tumors had the poorest prognosis (P = 0.001). Prompted multi-parameter comprehensive analysis of prognosis in the prognosis of the tumor has very important practical value.