论文部分内容阅读
T-2毒素是单端孢霉烯族毒素之一,可由多种真菌产生。该毒素毒性强烈,在自然界中广泛存在,严重危害人畜健康。1992年封剑楠等报道,浙江桐乡县部分居民误食T-2毒素污染(180～418×10~(-9))的霉变大米,发生急性食物中毒。目前认为,本世纪30、40年代发生于前苏联,死亡率高的“食物中毒性白细胞减少症”(A limentery Toxic Aleuki-a,ATA)和T-2毒素密切相关。近年杨健伯等提出,T-2毒素对食用粮(小麦、玉米)的污染导致了另一种地方病——大骨节病(KBD)的发生。 早在1973年,FAO/WHO就将单端孢霉烯族毒素列为最危险的天然存在的食品污染源之一;“黄雨中毒”事件发生之后,关于T-2毒素的研究更为
T-2 toxins are one of the trichothecene toxins that can be produced by a variety of fungi. The toxin is highly toxic and widespread in nature, seriously endangering the health of humans and animals. In 1992, Sean Kennan et al. Reported that some residents of Tongxiang County, Zhejiang Province, ingested mildew rice contaminated with T-2 toxin (180-418 × 10 -9), causing acute food poisoning. It is currently believed that the high mortality rate of A limentery Toxic Aleuki-a (ATA) and T-2 toxin that occurred in the Soviet Union in the 30s and 40s of this century are closely related. In recent years, Yang Jianbo et al. Suggested that the contamination of food grains (wheat and corn) by T-2 toxin caused another endemic disease, Kaschin-Beck disease (KBD). As early as 1973, the WHO / WHO listed the trichothecene toxin as one of the most dangerous sources of naturally occurring food contamination. After the “Huangyu poisoning” incident, the study on T-2 toxin was even more