治疗某一感染的首选药物,通常是对该致病微生物最有效的药物,或者是几个有效药物中毒性最低的药物。感染部位常常会改变药物的选择;某一药物可能比其他药物更易透入胆汁、尿或脑脊液。患者的临床状况,如肾或肝功能不全,或者对青霉素产生 The drug of choice for the treatment of an infection is usually the one that is most effective against the pathogenic microorganism or the least toxic of any of the available drugs. The site of infection often changes the choice of drug; a drug may penetrate bile, urine or cerebrospinal fluid more readily than other drugs. The patient’s clinical condition, such as renal or hepatic insufficiency, or penicillin production