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目的探讨血液灌流(HP)对救治重度急性有机磷农药中毒(AOPP)的疗效。方法回顾性分析64例重度急性有机磷农药中毒患者的临床资料,将其分为血液灌流组(治疗组)和常规治疗组(对照组)。两组患者均常规给予洗胃、导泻及应用阿托品、胆碱酯酶复能剂等常规综合治疗,治疗组同时行血液灌流。结果治疗组患者的阿托品用量、胆碱酯酶复活时间、清醒时间和住院天数等均明显低于对照组。结论在常规治疗方法的基础上,应用血液灌流技术救治重度急性有机磷农药中毒,疗效显著。
Objective To investigate the effect of hemoperfusion (HP) on the treatment of severe acute organophosphorus pesticide poisoning (AOPP). Methods The clinical data of 64 patients with severe acute organophosphorus pesticide poisoning were retrospectively analyzed. They were divided into hemoperfusion group (treatment group) and conventional treatment group (control group). Both groups were routinely given gastric lavage, cathartic and atropine, cholinesterase and other conventional comprehensive treatment, the treatment group at the same time hemoperfusion. Results Atropine consumption, cholinesterase resurrection time, awake time and hospitalization days in the treatment group were significantly lower than those in the control group. Conclusion On the basis of routine treatment, the application of hemoperfusion technique in the treatment of severe acute organophosphorus pesticide poisoning has obvious curative effect.