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目的：了解成都地区儿童葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症的发病概况。方法收集2014~2015年在我院进行G6PD活性检测的6000例儿童的血样标本，采用紫外速率法进行G6PD活性检测。结果在6000例受检儿童中，G6PD缺乏症总的检出率为5.92%（355/6000），其中男性的检出率为6.96%（277/3980），女性的检出率为3.86%（78/2020），两组的检出率具有明显的统计学差异。结论成都地区G6PD缺乏症的发病率较高，广泛开展产前G6PD活性筛查，对减少儿童G6PD缺乏症发病率有一定的帮助。“,”ObjectiveTo review the childen of Glucose-6-phosphate dehydrogenase(G6PD) deficiency in Chendu area.Methods6000 cases of outpatients in the hospital were collected from 2014 to 2015.The activity of G6PD was determined by using ultra-violet rate method.ResultsTotal incidence rate of the 6000 children G6PD deficiency was5.92%(355/6000), while the male was 6.96%(277/3980), the female was3.86%(78/2020). The detection rate of the two groups have significant statistical difference.ConclusionThe incidence of G6PD deficiency were high in Chendu area. Therefore ,the early prenatal G6PD screening have some help to reduce the incidence of G6PD deficiency in children.