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【目的】初步探讨儿童哮喘与生命早期羅患呼吸道疾病之间的关系。【方法】共301例哮喘儿童纳入研究,301例非喘息性疾病患儿作为对照。采用向家长书面问卷调查方法询问各组婴儿围生期因素、家族史及既往感染性疾病等资料进行综合调查。【结果】本地区儿童早期呼吸道感染和中耳炎患病次数、既往毛细支气管炎、肺炎和支气管炎、新生儿期接受NICU治疗、男性、哮喘家族史、过敏体质以及被动吸烟等均与儿童后期哮喘发病密切相关,而呼吸道感染和中耳炎的发病年龄则与哮喘的关系不明显。【结论】本地区儿童早期呼吸道感染和中耳炎患病次数与儿童哮喘的发生发展以及发作程度密切相关,具有上述高危因素的儿童是本地区制定哮喘预防措施重点关注人群。
【Objective】 To investigate the relationship between childhood asthma and respiratory diseases in early life. 【Methods】 A total of 301 asthmatic children were included in the study and 301 non-asthmatic children were used as controls. A written survey of parents asked the method of perinatal infant infants, family history and past infectious diseases and other data for a comprehensive survey. 【Results】 The prevalence of early childhood respiratory infection and otitis media in children, bronchiolitis, pneumonia and bronchitis in the past, NICU in neonatal period, males, family history of asthma, allergic constitution and passive smoking were all significantly correlated with the incidence of childhood asthma Is closely related to the age of onset of respiratory tract infection and otitis media is not obvious with the relationship between asthma. 【Conclusion】 The prevalence of early childhood respiratory infection and otitis media in children in this area is closely related to the occurrence and development of asthma in children and the extent of the seizures. Children with the above risk factors are the focus groups for the development of asthma prevention measures in this region.