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妊娠期肝内胆汁淤积症（ＩＣＰ）的病因和发病机理不明，临床上ＩＣＰ与妊高征的关系密切［１］。免疫功能失调和自身免疫反应异常是妊高征的重要病理变化［２４］，免疫因素与ＩＣＰ发病的关系也引起了注意。本研究测定正常妊娠晚期孕妇、合并或不合并妊高征的ＩＣＰ患者的
Etiology and pathogenesis of intrahepatic cholestasis of pregnancy (ICP) is unknown, and ICP is closely related to PIH [1]. Immune dysfunction and autoimmune reaction abnormalities is an important pathological change of pregnancy-induced hypertension [2-4], immune factors and the incidence of ICP also attracted attention. This study examined pregnant women with normal late pregnancy, with or without pregnancy-induced hypertension in ICP patients