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目前,对慢性宫颈炎伴鳞状上皮不同程度不典型增生的病理诊断,主要是依据不典型增生累及上皮的厚度而确定。但这种诊断指标不易准确掌握,而且不易统一。未实验的目的是想用体视学的方法,寻找一种定量指标,以便较为准确地区分上述4种病变。我们选择4个指标:核密度、核大小、核形态及核浆比。其中核密度、核大小和核浆比例3项指标随着不典型增生的程度的增高,均值逐渐增大,而且经统计学处理有显著性差异(P<0.0001)。实验结果表明,用定量指标能够更准确地区分上述病变。
At present, the pathological diagnosis of atypical hyperplasia of chronic cervicitis with squamous epithelium is mainly based on the thickness of atypical hyperplasia involving the epithelium. However, this diagnostic indicator is not easy to grasp accurately, and not easy to unify. The purpose of the non-experimental is to use stereological methods to find a quantitative index in order to more accurately distinguish the four kinds of lesions. We choose four indicators: nuclear density, nuclear size, nuclear morphology and nuclear ratio. The nuclear density, nuclear size and nuclear plasma ratio of three indicators with the degree of atypical hyperplasia increased, mean gradually increased, and statistically significant (P <0.0001). Experimental results show that using quantitative indicators can more accurately distinguish the above lesions.