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弓形虫(Toxoplasma gondii)是一种专性细胞内寄生的机会致病原虫,引起严重的人兽共患弓形虫病。在机体免疫功能正常情况下,弓形虫多为隐性感染,而在免疫缺陷人群如艾滋病患者,弓形虫可对患者的中枢神经系统、呼吸系统、消化系统、内分泌系统、心血管系统等产生不同程度的损害。艾滋病合并弓形虫感染的研究主要集中在流行病学调查和诊断方法、对机体的影响、动物模型研究和治疗药物等方面,本文就艾滋病合并弓形虫感染研究进展进行综述。
Toxoplasma gondii is a potent intracellular zoonotic pathogen of intracellular parasites that causes severe zoonotic zoonosis. Toxoplasma gondii are mostly latent infection in normal immune function, while in immunocompromised population such as AIDS, Toxoplasma gondii can produce different effects on the central nervous system, respiratory system, digestive system, endocrine system and cardiovascular system of patients Degree of damage. AIDS and Toxoplasma gondii infection mainly focus on epidemiological investigation and diagnosis methods, the impact on the body, animal models and the treatment of drugs, etc., this article reviews the progress of HIV infection with Toxoplasma infection.