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目的比较美沙拉嗪与柳氮磺吡啶治疗溃疡性结肠炎的效果。方法选取安达市医院2012年8月—2014年8月收治的76例溃疡性结肠炎患者,根据入院顺序分为治疗组与对照组,每组38例。治疗组采用美沙拉嗪治疗,对照组采用柳氮磺吡啶治疗,比较两组的临床效果及不良反应发生情况。结果治疗组的总有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论美沙拉嗪治疗溃疡性结肠炎的效果优于柳氮磺吡啶,且不良反应少。
Objective To compare the effects of mesalazine and sulfasalazine in the treatment of ulcerative colitis. Methods A total of 76 patients with ulcerative colitis admitted to Anda Hospital from August 2012 to August 2014 were divided into treatment group and control group according to admission sequence, with 38 patients in each group. The treatment group was treated with mesalazine, the control group was treated with sulfasalazine, and the clinical effects and adverse reactions of the two groups were compared. Results The total effective rate of the treatment group was higher than that of the control group, and the incidence of adverse reactions was lower than that of the control group (P <0.05). Conclusion Mesalazine is superior to sulfasalazine in the treatment of ulcerative colitis with less adverse reactions.