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评价精纯抗栓酶对急性脑梗塞的临床疗效。方法:采用随机、开放、对照的方法将急性脑梗塞患者126例分为治疗组对例与对照组56例,治疗组应用精纯抗栓酶首次20U,以后10U,加入生理盐水250ml静脉滴注,隔日给药,4次为一疗程;对照组应用蝮蛇抗栓酶常规治疗。结果:治疗15天后治疗组总有效率为84.29%,对照组为64.29%(P<0.01),治疗后纤维蛋白原降低治疗组比对照组更明显(P<0.01)。结论:精纯抗栓酶治疗急性脑梗塞疗效确切,副反应少。
To evaluate the clinical efficacy of pure antithrombin against acute cerebral infarction. Methods: 126 patients with acute cerebral infarction were divided into treatment group (56 cases) and control group (56 cases) by random, open and controlled method. The treatment group was treated with pure antithrombotic enzyme for the first time by 20U, then 10U, , Administered on the next day, 4 times for a course of treatment; control group applied viper antithrombin routine treatment. Results: After 15 days of treatment, the total effective rate was 84.29% in the treatment group and 64.29% in the control group (P <0.01). After treatment, the fibrinogen reduction group was more obvious than the control group (P <0.01) ). Conclusion: Antithrombotic enzyme is effective in treating acute cerebral infarction with few side effects.