临床上因注射破伤风抗毒素(下简称TAT)所致过敏性休克或死亡,国内外已有较多报道,但皮试阴性而注射TAT后发生过敏性休克病例较少见。我们最近先后遇到3例,报道如下。病例报告 [例1] 女,4岁。患儿因外伤在卫生所作TAT皮试阴性后肌注TAT1500单位,注后2分钟出现烦躁、气短、全身皮肤瘙痒,并可见黄豆大红色丘疹。考虑TAT过敏,立即应用地塞米松、苯海拉明、肾上腺素等抢救治疗。约30分 Clinically due to injection of tetanus antitoxin (hereinafter referred to as TAT) caused by anaphylactic shock or death, there have been more reports at home and abroad, but skin test negative after injection of TAT occurred after anaphylactic shock rare. We have recently encountered three cases, reported as follows. Case Report [Example 1] Female, 4 years old. Children with trauma in the health TAT skin test negative after intramuscular injection of TAT1500 units, 2 minutes after the note irritability, shortness of breath, systemic skin itching, and visible red bean papules. Consider TAT allergy, immediate application of dexamethasone, diphenhydramine, epinephrine and other rescue treatment. About 30 minutes