口蹄疫为主要的动物传染病之一,病毒侵袭反刍动物和猪,易于传播,几乎遍及世界各地。预防此病的疫苗为灭活疫苗,在幼地鼠等组织培养上制备。虽然疫苗有一定预防效果,也存有缺点:热稳定性不好,尤其热带地方使用受限制;最近在欧洲由于疫苗灭活不当而造成该病流行。近些年来有些 Foot-and-mouth disease is one of the major zoonotic diseases in which the virus infects ruminants and pigs and spreads easily, reaching almost all over the world. Vaccine to prevent the disease inactivated vaccine, in young mice and other tissue culture preparation. Although the vaccine has some preventive effects, there are also disadvantages: poor thermal stability, especially in tropical places; recently the epidemic in Europe due to improper vaccine inactivation. Some in recent years