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本文报告精神障碍型钩体病21例。临床表现可分为急性脑器质性综合征型、慢性脑器质性综合征型、类分裂症型及类神经症型。推想本型钩体病主要由钩体直接损害脑实质所致,但不排除脑组织对钩体产生变态反应这一机制。指出对来自疫区有发热、神经系统体征、意识障碍或智能损害者应常规做钩体血清学检查。青霉素及激素治疗有效。本组20例曾误诊,应提高对本病的认识及警惕。
This article reports 21 cases of leptospirosis with mental disorders. Clinical manifestations can be divided into acute cerebral organic syndrome, chronic cerebral organic syndrome, schizophrenia and neurosis. It is assumed that this leptospirosis is mainly caused by that the hook body directly damages the parenchyma of the brain, but does not exclude the mechanism that the brain tissue produces an allergic reaction to the hook body. Pointed out that the epidemic area from the fever, nervous system signs, disturbance of consciousness or intelligent damage should be routine hook body serology. Penicillin and hormone therapy effective. 20 cases of this group have been misdiagnosed, should raise awareness of the disease and vigilance.