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高肌酸磷酸激酶(CPK)一般见于心肌梗塞(MI)、肌肉疾患和中枢神经系疾病。1969年 Veletz-Garcia最先在糖尿病酮症酸中毒发现 CPK 升高。本文以11例伴高 CPK 血症的糖尿病急性代谢紊乱为观察对象,探讨其成因及意义。入院时 CPK MM 型浓度在200IU/L 以上者11例,其中糖尿病酮症1例,酮症酸中毒8例,非酮症高渗性昏迷2例,以上为 A 组;入院时 CPK MM 型浓度在200IU/L 以下者30例,其中酮症14例,酮症
High creatine phosphokinase (CPK) is commonly found in myocardial infarction (MI), muscular disorders and central nervous system disorders. In 1969, Veletz-Garcia first found CPK increased in diabetic ketoacidosis. In this paper, 11 cases of acute metabolic disorders associated with high CPK hyperlipidemia as the object of observation, to explore its causes and significance. Admission CPK MM concentration of 200IU / L or more in 11 cases, including diabetic ketosis in 1 case, 8 cases of ketoacidosis, nonketotic hyperosmolar coma in 2 cases, the above is Group A; admission CPK MM concentration In 200IU / L the following 30 cases, of which ketosis 14 cases, ketosis