论文部分内容阅读
目的:了解宁波地区手足口病病人密切接触人群中肠道病毒的感染情况,为制定手足口病预防和控制策略提供科学的依据。方法:选取海曙、奉化、镇海三个点,每个月采集手足口病人及其密切接触者的标本,进行肠道病毒核酸荧光定量PCR检测,对结果进行统计学分析。结果:肠道病毒感染率的高低在不同地区(P>0.05)和不同年龄组间(P>0.05)均无明显差异。EV71病例的密接继发率和CoxA16病例的差别有统计学意义(P<0.01)。结论:在手足口病病人密切接触人群中存在肠道病毒感染情况,EV71型病毒的传播力要高于CoxA16。
Objective: To understand the infection of enteroviruses in hand, foot and mouth disease patients in close contact with the population in Ningbo, and to provide a scientific basis for the prevention and control strategy of HFMD. Methods: Three spots of Haishu, Fenghua and Zhenhai were selected. Samples of hand-foot-mouth patients and their close contacts were collected every month. The results were analyzed by quantitative real-time PCR. Results: The infection rate of enterovirus was not significantly different between different regions (P> 0.05) and different age groups (P> 0.05). There was a significant difference between the close incidence of EV71 and CoxA16 (P <0.01). CONCLUSIONS: Enterovirus infection is present in close contacts of HFMD patients, and the EV71 virus is more infectious than CoxA16.