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目的比较小儿行心脏彩超检查前减少睡眠配合咪唑安定或水合氯醛的镇静效果及安全性。方法随机将112例先天性心脏病患儿分为A、B两组,每组56例。A组于心脏彩超检查前采取减少睡眠配合咪唑安定0.5～0.75mg/kg,B组则采取检查前减少睡眠配合10%水合氯醛50～80mg/kg口服。观察患儿给药后入睡时间、镇静效果、清醒时间、不良反应、并发症等情况。结果 A组55例患儿能在30min内进入睡眠,镇静成功率98.2%,B组51例患儿能在30min内进入睡眠,镇静成功率91.1%。其中B组有7例患儿出现呕吐、苏醒延迟、活动过度等并发症。Ramsay评分差异有统计学意义。结论心脏彩超检查前减少患儿睡眠配合咪唑安定较配合10%水合氯醛更安全、有效。
Objective To compare pediatric cardiac echocardiography before check to reduce the sedation with imidazole diazepam or chloral hydrate sedation and safety. Methods 112 cases of children with congenital heart disease were randomly divided into A and B groups, 56 cases in each group. A group to reduce sleep before taking ultrasound combined with midazolam 0.5 ~ 0.75mg / kg, B group before taking the test to reduce sleep with 10% chloral hydrate 50 ~ 80mg / kg orally. Observe the children after going to sleep time, sedation, awake time, adverse reactions, complications and so on. Results 55 children in Group A were able to sleep within 30 minutes. The success rate of sedation was 98.2%. 51 children in Group B were able to sleep within 30 minutes and the sedation success rate was 91.1%. In group B there were 7 cases of children with vomiting, delayed recovery, hyperactivity and other complications. Ramsay score difference was statistically significant. Conclusions It is safer and more effective to reduce children sleep with midazolam than with 10% chloral hydrate before the echocardiography.