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本本用ABC法对36例各型慢性肝炎患者肝活检标本进行了HBsAg、HBcAg的检测。检出HBsAg和/或HBcAg12例,总阳性率32.4％。发现慢活肝不仅HBV复制标志检出率高达44.0％(11/25),且HBV复制活跃。还发现HBV复制程度与脏活动性病变程度基本呈平行关系,呈强阳性显色者,慢活肝都属中、重型。本文还见HBV复制活跃,病变活跃,肝内HBsAg主要呈弥漫型,HBcAg主要呈胞核,细浆型。上述结果提示:HBV复制和肝炎的病变活动有关。
The ABC method was used to detect HBsAg and HBcAg in 36 liver biopsy specimens of various types of patients with chronic hepatitis. 12 cases of HBsAg and / or HBcAg were detected, the total positive rate was 32.4%. It was found that not only the detection rate of HBV replication markers was as high as 44.0% (11/25), but HBV replication was also active. Also found that the extent of HBV replication and dirty active lesions basically parallel relationship was strongly positive color were slow living liver are medium and heavy. This article also see the active HBV replication, active lesions, the main was HBsAg intrahepatic diffuse type, HBcAg was mainly nuclear, fine plasma type. The above results suggest that: HBV replication and hepatitis lesions related.