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目的大量的研究表明；运动尤其是力竭性运动后血液的生理生化特性、宏观血液流变特性以及红细胞、血小板流变特性将发生明显的改变；运动和免疫有着密切的关系；研究表明，过量的运动对免疫系统造成损伤、基干白细胞特别是ＰＭＮｓ（Ｐｏｌｙｍｏｒｐｈｏｎｕｃｌｅａｒ ｎｅｕｔｒｏｐｈｉｌｓ，ＰＭＮｓ）的特殊生理功能地位，本文将对运动力竭后微循环中白细胞粘附行为进行研究，更深一步探讨运动性疲劳机制。方法以游泳方法建立大鼠模拟运动力竭模型，运用活体显微电视录像系统观察肠系膜微循环并录像。选择单个无分枝的毛细血管后微静脉和细静脉作为研究对象，运用计算机图像处理系统回放分析肠系膜微循环观察图像，测定微血流动力学参数；管径（Ｄ）、白细胞粘附数目、白细胞滚动速度（Ｖｗｂｃ）、白细胞变形指数（ＤＩ）。结果观察到在不同的血管管径范围下所对应的大鼠运动力竭后白细胞粘附在静脉／毛细血管内皮细胞表面上的数目明显高于正常组．大鼠运动力竭后肠系膜微静脉中白细胞的滚动速度由正常状态的８８．９９±２６．３２（μｍ／ｓ）降为５４．２４±１７．２９（μｍ／ｓ），减少了３９，０４％，差别显著（Ｐ＜０．０５）；大鼠运动力竭后肠系成微循环中白细胞变形指数由正常状态的
Purpose A large number of studies have shown that the physiological and biochemical characteristics of blood, macroscopic hemorheological properties, and erythrocyte and platelet rheology will be significantly changed after exercise, especially after exhaustive exercise. Exercise and immunity are closely related. Studies have shown that excess Of the exercise on the immune system damage, basic white blood cells, especially PMNs (PMNs) of the special physiological function of the position, this article will be after exhaustive exercise microcirculation white blood cell adhesion behavior to further explore sports fatigue mechanism. Methods The model of exhaustive exercise in rats was established by swimming, and the mesenteric microcirculation was observed by live video system. A single branchless capillary venules and venules were selected as the research object, the mesenteric microcirculation observation images were analyzed by computer image processing system, and the micro-hemodynamics parameters were measured. The diameter (D), the number of leukocyte adhesion, Leukocyte rolling velocity (Vwbc), leukocyte deformability index (DI). Results It was observed that the number of leukocytes adhering to the surface of venous / capillary endothelial cells was significantly higher than that of the normal group after exhaustion of rats corresponding to different vascular diameter ranges. Rolling speed of mesenchymal cells in mesenteric venules decreased from 88.99 ± 26.32 (μm / s) to 54.24 ± 17.29 (μm / s) in rats after exercise exhaustion, decreasing by 39,04 %, The difference was significant (P <0.05); after exhaustive exercise, the leucocyte deformability index