目的：探讨电化学治疗中晚期乳腺癌的临床效果。方法：采用特制的ＢＫ９２型治疗仪和铂金针，在局麻下将铂金针插入肿瘤内，再连接在治疗仪上进行通电治疗。结果：接受电化学治疗的１０５例中晚期乳腺癌中７４例为原发性乳腺癌，３１例是乳癌术后局部复发癌。１年内疗效为ＣＲ３５２％；ＰＲ４３８％；ＮＣ１３３％；ＰＤ７６％。将ＣＲ＋ＰＲ评为有效，占７９０％。经５年随访：１年生存率８９５％；２年生存率为６９５％，５年生存率为５０４％。结论：电化学可治疗中晚期乳腺癌，尤其是对术后复发癌有较好疗效。 Objective: To investigate the clinical effect of electrochemical treatment of advanced breast cancer. METHODS: A special BK92-type therapeutic apparatus and platinum needles were used to implant platinum needles into the tumor under local anesthesia, and then connected to the therapeutic apparatus for electrification treatment. RESULTS: Of the 105 patients with advanced breast cancer undergoing electrochemical therapy, 74 were primary breast cancer and 31 were local recurrence cancer after breast cancer surgery. The curative effect within one year was CR352%; PR438%; NC133%; PD76%. CR+PR was rated as effective, accounting for 79.0%. After 5 years of follow-up, the 1-year survival rate was 89.5%, the 2-year survival rate was 69.5%, and the 5-year survival rate was 50.4%. Conclusion: Electrochemistry can treat advanced breast cancer, especially for postoperative recurrence of cancer.