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目的了解门诊高危人群男性人乳头瘤病毒(HPV)亚临床感染和隐性感染情况及亚型分布,为制定HPV感染的预防策略提供依据。方法采用核酸分子快速导流杂交基因芯片技术对1206例性病门诊高危男性人群进行HPV分型检测。结果 HPV阳性342例,阳性率为28.36%;其中低危型174例,占50.88%,常见亚型为HPV11,HPV6和HPV42;高危型168例,占49.12%,常见亚型为HPV16,HPV52,HPV58和HPV33。342例阳性患者,单一感染67.54%(231/342),二重感染21.05%(72/342),多重感染11.40%(39/342)。结论本地区高危男性人群亚临床和隐性感染率较高,以HPV11,6,16,52,58,33等亚型为主;感染者以单一亚型为主。
Objective To understand the subclinical and sub-genotype distribution of male human papillomavirus (HPV) in high-risk outpatients and to provide evidence for the prevention of HPV infection. Methods Rapid genotyping of nucleic acid molecules was used to detect genotypes of HPV in 1206 high-risk male patients in STD clinics. Results The positive rate of HPV was 342 cases (28.36%), of which 174 cases were low-risk type (accounting for 50.88%). The common subtypes were HPV11, HPV6 and HPV42; 168 cases were high-risk, accounting for 49.12% HPV58 and HPV33.342 cases of positive patients, a single infection 67.54% (231/342), double infection 21.05% (72/342), multiple infections 11.40% (39/342). Conclusion The prevalence of subclinical and latent infections in high-risk males in this area is high, with HPV11, 6, 16, 52, 58 and 33 as the main subtypes;