化脓性中耳炎的反复感染或久治不愈,一直是耳科临床工作者感到棘手的问题。多种病菌复合感染是治疗困难的因素之一,其中厌氧菌的致病意义越来越为人们所重视。有人发现久治不愈者,取中耳脓性分泌物做普通细菌培养无菌生长约占20～30％,认为其感染多为无芽胞厌氧菌(non-spore-forming anaerobic bacteria)引起。无芽胞厌氧菌为人体寄生数量很大的条件致病菌,广泛分布于皮肤、口咽、消化道及女性生殖道等处,一旦条件适合,便可引起感染。临床常见有腹腔感染、肝脓肿、口腔感染、女性生殖 Repeated infections or prolonged suppurative otitis media has been a problem for otological clinicians. A variety of bacteria and compound infection is one of the difficult factors in treatment, anaerobic bacteria pathogenic significance of more and more attention. It was found that those who cured a long time, take the middle ear purulent secretions do ordinary bacterial culture of sterile growth accounts for about 20 to 30%, that the infection is mostly caused by non-spore-forming anaerobic bacteria (non-spore-forming anaerobic bacteria). Bacillus subtilis anaerobic bacteria parasites for the human body is a large number of opportunistic pathogens, widely distributed in the skin, oropharynx, digestive tract and the female reproductive tract and other places, once the conditions are right, can cause infection. Clinical common abdominal infection, liver abscess, oral infections, female reproduction