肾上腺糖皮质激素(GC)要发挥生理效应必须与相应的糖皮质激素受体(GCR)特异性结合。作者采用放射配体结合法的一点分析法、以~3H-地塞米松([~3H]-Dex)为配体,测定了3例肾上腺皮质功能减退症病人8:00时静脉血混合白细胞GCR。其中2例为Addison氏病,1例为双侧肾上腺皮质增生术后患 Glucocorticoid glucocorticoid (GC) to play a physiological effect must be associated with the corresponding glucocorticoid receptor (GCR) specific binding. The authors used radioligand binding assay, 3H-dexamethasone ([~ 3H] -Dex) as a ligand, measured in 3 cases of adrenal hypofunction in patients with venous blood mixed white blood cells at 8:00 GCR . Two cases were Addison’s disease and one case was bilateral adrenal hyperplasia