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目的通过大样本流行病学调查,了解目前北京地区儿童青少年血脂现状及血脂紊乱的患病水平,以期为动脉粥样硬化的早期预防提供科学依据。方法采用整群抽样的方法,于2004-04—2004-10组织流行病学调查组,对北京市7个城、郊区县的19 593名6-18岁儿童青少年进行现场调查,对其空腹末梢血总胆固醇(TC)和甘油三酯(TG)进行检测,从而对北京地区6-18岁儿童青少年的血脂紊乱情况进行横断面流行病学研究。结果北京地区儿童高脂血症总患病率为9.61%(1 874/19 501),其中TC增高者占调查者的1.21%(236/19 501),TG增高者占8.79%(1 714/19 501),TC、TG同时增高者占0.39%(76/19 501);城区儿童高脂血症患病率10.55%(1 053/9 978),男生患病率10.16%(503/4 950),女生患病率10.94%(550/5 028);郊区儿童该病患病率8.62%(821/9 523),男生患病率6.11%(294/4 811),女生患病率11.18%(527/4 712)。结论北京市儿童高脂血症的现患率较前明显增高,且具地区、年龄、性别差异的流行病学特征。
Objective To understand the prevalence of dyslipidemia and the prevalence of dyslipidemia in children and adolescents in Beijing in order to provide a scientific basis for the early prevention of atherosclerosis through large sample epidemiological investigation. Methods A cluster sampling method was used to survey 19 593 adolescents aged 6-18 years in 7 cities and suburban counties in Beijing from April 2004 to October 2004 with the Epidemiological Investigation Team. Blood total cholesterol (TC) and triglyceride (TG) were tested in order to conduct cross-sectional epidemiological studies of dyslipidemias among adolescents aged 6-18 years in Beijing. Results The overall prevalence of hyperlipidemia in children was 9.61% (1874/19501) in Beijing. Among them, the increase of TC was 1.21% (236/19501) and the higher of TG was 8.79% (1 714 / The prevalence of hyperlipidemia in urban areas was 10.55% (1053/9 978), while the prevalence of boys was 10.16% (503/4 950 ), The prevalence rate of girls was 10.94% (550/5 028); that of suburban children was 8.62% (821/9 523), that of boys was 6.11% (294/4 811) and that of girls was 11.18% (527/4 712). Conclusions The prevalence of hyperlipidemia in children in Beijing was significantly higher than that in the previous years, with epidemiological characteristics of regional, age and gender differences.