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目的检测吸烟的慢性牙周炎患者牙周基础治疗前后龈沟液内NO含量,与不吸烟患者的进行比较,结合牙周炎临床症状的改善情况,探讨吸烟与牙周炎的关系。方法在口腔内科门诊选取患有慢性牙周炎患者20例,随机分为吸烟组和不吸烟组。在牙周炎治疗前后分别采集龈沟液标本,免疫荧光法检测龈沟液NO含量进行分析,同时记录牙周炎临床症状的改善程度。结果两组经牙周基础治疗后NO含量均有明显下降,吸烟者的含量显著高于不吸烟者,牙周炎临床指标的变化表明吸烟者治疗前后的变化显著小于不吸烟者。结论吸烟与导致牙周炎相关且影响牙周炎的治疗效果。
Objective To detect the content of NO in gingival crevicular fluid of patients with chronic periodontitis before and after periodontal treatment and to compare the improvement of clinical symptoms with periodontitis to explore the relationship between smoking and periodontitis. Methods Twenty patients with chronic periodontitis were selected in oral clinic and randomly divided into smoking group and non-smoking group. Gingival crevicular fluid samples were collected before and after periodontitis treatment, and the content of NO in gingival crevicular fluid was detected by immunofluorescence method. Meanwhile, the clinical symptom improvement of periodontitis was recorded. Results After the periodontal treatment, the content of NO in both groups decreased significantly, the content of smokers was significantly higher than that of non-smokers. The changes of clinical indicators of periodontitis showed that the change of smokers before and after treatment was significantly less than that of non-smokers. Conclusions Smoking is associated with periodontitis and affects the treatment of periodontitis.