The Cenozoic evolution history of Guizhou Province, which is located on the southeastern flank of the Qinghai-Tibet Plateau, is unclear because of the lack of sedimentation records. The red weathering crusts widespread on the Yunnan-Guizhou Plateau may bear critical information about their evolution history. This work firstly determined the ages of four red weathering crusts in eastern, central and northern Guizhou. The material used in fission track dating is well-crystallized quartz occurring in many in-situ weathering crusts of carbonate rocks. The results showed that the fission track ages of quartz vary over a wide range from 1 to 25 Ma in the four profiles, significantly younger than the ages of the Triassic and Cambrian parent rocks. In combination with the evolution history of the regional geology during the period from 25 to 1 Ma, the ages of quartz can exclude the possibility that the origin of quartz has nothing to do with primary clastic minerals in parent rocks, authigenesis during diagenesi