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目前,无机纳米材料模拟生物酶催化活性的报道得到了纳米技术领域的广泛重视,模拟葡萄糖氧化酶的纳米金和过氧化物酶的磁性纳米颗粒就是其中的典型代表.与常规的生物酶相比,无机纳米颗粒稳定性较强,受酸碱、温度等因素的影响较小;而且易于制备和纯化,生产成本低,容易被标记和修饰,具有广泛的研究和应用前景.此外,由于无机纳米材料低毒、生物相容性好的特点,这些纳米颗粒还有望在生命体的生理代谢过程中发挥重要的作用.相关的研究已经证明了无机纳米材料的酶学性质,并在催化机理层面进行了初步的探讨.本文综述了无机纳米材料在生物酶催化活性方面的研究进展与应用前景,希望能够为此类纳米材料更加科学合理地运用于生物催化领域提供参考.
At present, inorganic nanomaterials have been widely reported in the fields of nanotechnology due to the simulation of the catalytic activity of biological enzymes, and the typical examples of magnetic nanosized gold nanoparticles and peroxidase that mimic glucose oxidase are typical examples of these. , Inorganic nanoparticles have strong stability and are less affected by factors such as acid and alkali, temperature, etc. And they are easy to prepare and purify, have low production cost, are easy to be labeled and modified, and have extensive research and application prospects. In addition, Low toxic and biocompatible materials, these nanoparticles are also expected to play an important role in the physiological metabolism of living organisms.Related studies have demonstrated the enzymatic properties of inorganic nanomaterials and their catalytic mechanism at the level of This paper reviews the research progress and application prospect of inorganic nanomaterials in the field of biological enzyme catalytic activity, hoping to provide a reference for the application of such nanomaterials in the field of biocatalysis more scientifically and reasonably.