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目的：对核糖核酸Ⅱ联合放化疗治疗鼻咽癌的疗效进行观察。方法：68例鼻咽癌患者随机分为核糖核酸Ⅱ联合放化疗组和单纯放化疗组各34例。核糖核酸Ⅱ联合放化疗组在缓解率、生活质量改善都比单纯放化疗组明显要好，而且在白细胞减少、急性口腔粘膜反应及颈部皮肤反应的毒副反应程度上相对轻。结论：核糖核酸Ⅱ联合放化疗治疗鼻咽癌能有效地改善患者生活质量，减轻了毒副反应，可作为鼻咽癌治疗的常用方法。“,”Objective To RNAⅡ combined radiation and chemotherapy to observe curative effect for the treatment of nasopharyngeal carcinoma.Methods 68 nasopharyngeal carcinoma patients were randomly divided into RNAⅡ combined radiation and chemotherapy group and pure radiation and chemotherapy group (n = 34). RNAⅡ combined radiation and chemotherapy group in remission rate and life quality improvement was obviously better than pure radiation and chemotherapy group, and in leukopenia, acute oral mucosa reaction and the side reaction of the neck skin reaction extent relatively light.Conclusions RNAⅡ combined radiation and chemotherapy treatment of nasopharyngeal carcinoma, can effectively improve patient quality of life, reduce the adverse reaction, the commonly used method can be used as treatment of nasopharyngeal carcinoma (NPC).