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目的 :观察重组组织型纤溶酶原激活剂 ( rt- PA)对急性心肌梗塞的治疗效果。方法 :对 89例急性心梗患者口服肠溶阿司匹林 30 0 mg或巴米尔 0 .3g泡水饮 ,然后给 rt-PA1 0 mg,2 min内静脉推注完毕 ,之后给 rt- PA90 mg在 1 2 0 min内静脉滴注随即给低分子肝素 5 0 0 0 IU皮下注射 ,每 1 2 h1次 ,连用 7d。结果 :<6h入院者 37例 ,再通 30例 ,再通率为83% ,6～ 1 2 h入院者 48例 ,再通 2 9例 ,再通率 62 % ,>1 2 h入院者 4例 ,再通 1例 ,再通率2 5 % ,总再通率为 67%。结论 :rt- PA治疗急性心肌梗塞再通率明显高于 UK,是目前比较理想溶栓用药
Objective: To observe the therapeutic effect of recombinant tissue plasminogen activator (rt-PA) on acute myocardial infarction. Methods: Eighty-nine patients with acute myocardial infarction were treated with oral administration of aspirin 30 0 mg or Bamil 0.3 g soaked in water and then given rt-PA1 0 mg for intravenous injection within 2 min, then given rt-PA 90 mg at 1 Immediately after intravenous drip infusion within 20 min to low molecular weight heparin 50,000 IU subcutaneous injection, every 1 2 h1 times, once every 7d. Results: In 6 h admission, 37 patients were recanalized and the recanalization rate was 83%. Among them, 48 patients were admitted from 6 to 12 h, 29 patients were recanalized, the recanalization rate was 62%, and the admission rate was> 12 h Cases, again in 1 case, the recanalization rate of 25%, the total recanalization rate of 67%. Conclusion: rt-PA treatment of recurrent rate of acute myocardial infarction was significantly higher than UK, is the ideal thrombolytic therapy