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单纯疱疹病毒(HSV)属于疱疹病毒属,为带囊膜的20面体立体对称的球形DNA病毒,直径150～200nm。分为HSV-1和HSV-2两个血清型。研究表明两型病毒在致病性、感染部位以及药物敏感性等方面均有明显差异。特别是HSV-2与子宫颈癌关系密切,因此,进行HSV分型不仅在疾病诊断及流行病学调查中具有重要意义,而且对HSV感染的预后估计、病情咨询以及临床药物选择等方面均有一定的实用价值。自从Plummer等(1964)根据HSV抗原性不同,将其分为两型以来,建立了许多分型
Herpes simplex virus (HSV) belongs to herpesvirus genus, which is a 20-dimentional spherical DNA virus with capsid membrane and has a diameter of 150-200 nm. Divided into HSV-1 and HSV-2 two serotypes. Studies have shown that two types of viruses in the pathogenicity, the site of infection and drug sensitivity and so there are significant differences. In particular, HSV-2 is closely related to cervical cancer. Therefore, the classification of HSV is not only significant in the diagnosis of diseases and epidemiological investigation, but also in estimating the prognosis of HSV infection, counseling of disease and clinical drug selection Certain practical value. Since Plummer et al. (1964) categorized them into two types based on the antigenicity of HSV, many subtypes have been established