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为查清日本糖尿病的自然史,我们对糖尿病患者进行了长期随访调查。结果不仅查清了糖尿病的预后、危险因素及死亡原因、还对过去25年间糖尿病死因变化情况进行了研究。对象为1960～1979年间在我中心就诊的NIDDM患者1939名(男1200名、女739名),截止1984年平均随访时间9.4年,根据就诊情况、调查表、居民注册照会三种方式来确认被随访者的生死情况,结果尚存者1435名、死亡503名、不明者1名。年平均死亡率男为31.4‰、女为22.0‰,男女均显示初诊年龄越大死亡率越高。另与大阪府死亡统计相比较O/E的比例男为1.69,女为1.74,糖尿病患者的死亡危险性比一般人高,同时可
To find out the natural history of diabetes in Japan, we conducted a long-term follow-up survey of diabetic patients. The results not only identified the prognosis, risk factors, and cause of death of diabetes, but also studied the changes in the cause of death of diabetes in the past 25 years. The target population was 1,939 NIDDM patients (1200 males and 739 females) who were admitted to our center between 1960 and 1979. The average follow-up time was 9.4 years in 1984. The diagnosis was based on the status of visits, questionnaires, and residents’ registration notes. The life and death of the follow-up person was 1,435 survivors, 503 deaths, and 1 unknown person. The average annual mortality rate was 31.4 in males and 22.0 in females. Both males and females showed that the higher the initial age, the higher the mortality rate. In addition, the O/E ratio was 1.69 for males and 1.74 for females compared with the death statistics in Osaka. The risk of death from diabetes was higher than that of ordinary people.