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目的探讨彩色多普勒超声检测颈动脉斑块稳定性和脑梗死关系。方法选择2008年10月-2010年10月英山县人民医院住院的68例脑梗死患者及同期该院门诊查体并经检查证实无脑梗死者50例作为对照组进行双侧颈动脉彩色多普勒超声检查,观察其斑块数目、性质及动脉血流参数。结果脑梗死组68例患者中57例检出有斑块形成,占83.8%;对照组50例检出9例斑块形成,共检出斑块20个,占18.0%,脑梗死组斑块形成率明显高于对照组,两组比较差异有统计学意义(P<0.05);脑梗死组软斑、硬斑及混合斑分别占检出斑块的48.4%、23.9%、32.6%,而对照组软斑、硬斑及混合斑分别占检出斑块的20.0%、70.0%、10.0%,两组两两比较,差异均有统计学意义(P<0.05);对照组CCA的PSV、EDV值分别为(66.20±8.20)cm/s、(8.21±3.33)cm/s,梗死组CCA的PSV、EDV值分别为(55.80±6.71)cm/s、(4.41±1.85)cm/s,两组血流参数两两比较,差异均有统计学意义(P<0.05);对照组ICA的PSV、EDV值分别为(57.30±7.22)cm/s、(8.87±3.26)cm/s,梗死组ICA的PSV、EDV值分别为(53.50±6.27)cm/s、(4.52±1.48)cm/s,两组血流参数两两比较,差异均有统计学意义(P<0.05)。结论颈动脉粥样斑块是造成脑梗死的重要原因,不稳定斑块是引起脑梗死重要危险因素。
Objective To investigate the relationship between carotid plaque stability and cerebral infarction by color Doppler sonography. Methods From October 2008 to October 2010, 68 patients with cerebral infarction hospitalized in the People’s Hospital of Yingshan County and 50 outpatients with cerebral infarction confirmed by examination at the same period were selected as the control group to carry out bilateral carotid coloration Pulsed ultrasound examination to observe the number of plaques, nature and arterial blood flow parameters. Results Of the 68 patients with cerebral infarction, 57 cases were detected with plaque formation, accounting for 83.8%. In the control group, 9 cases were detected with plaque formation, 20 plaques were detected, accounting for 18.0%. Cerebral infarction plaque The formation rate was significantly higher than the control group, the difference between the two groups was statistically significant (P <0.05); cerebral infarction group plaque, plaque and mixed plaques accounted for plaque detection 48.4%, 23.9%, 32.6%, respectively The control group showed 20.0%, 70.0% and 10.0% of plaque spot, plaque and mixed plaque respectively, the difference was statistically significant (P <0.05). The PSV, The EDV values were (66.20 ± 8.20) cm / s and (8.21 ± 3.33) cm / s, respectively. The PSV and EDV values of CCA in infarction group were (55.80 ± 6.71) cm / The PSV and EDV of ICA in control group were (57.30 ± 7.22) cm / s and (8.87 ± 3.26) cm / s, respectively, and infarction The PSV and EDV of group ICA were (53.50 ± 6.27) cm / s and (4.52 ± 1.48) cm / s, respectively. There was significant difference between the two groups in blood flow parameters (P <0.05). Conclusion Carotid artery plaque is an important cause of cerebral infarction, and unstable plaque is an important risk factor for cerebral infarction.