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目的：观察氟桂利嗪治疗抗结核药物链霉素及卡那霉素所产生的眩晕、耳鸣等毒性反应的效果。方法：氟桂利嗪治疗组２２例（男性２０例，女性２例；年龄３４±ｓ５ａ），用法为５ｍｇ，ｐｏ，ｑｎ，疗程２～３ｗｋ；并与传统疗法组１５例（男性１２例，女性３例；年龄３６±４ａ），进行对照观察。结果：氟桂利嗪治疗组的毒性反应症状全部于１０ｄ内消失，有效率为１００％，且未停用链霉素或卡那霉素；传统疗法组的症状１０ｄ内仅消失１例，占４％。结论：氟桂利嗪治疗组的疗效高，起效迅速，并能保障抗结核治疗的疗程用药。
Objective: To observe the effect of flunarizine on the toxic reaction of dizziness and tinnitus produced by antituberculosis drugs streptomycin and kanamycin. Methods: Flunarizine treatment group of 22 patients (20 males and 2 females; age 34 ± s5a), usage of 5mg, po, qn, course of 2 ~ 3wk; and traditional therapy group of 15 patients (12 males, 3 females; age 36 ± 4a), control observation. Results: All the symptoms of flunarizine treatment group disappeared within 10 days, the effective rate was 100%, and streptomycin or kanamycin was not stopped. In traditional therapy group, only one symptom disappeared in 10 days, accounting for 4%. Conclusion: The flunarizine treatment group has high curative effect and rapid onset of action, and can guarantee the anti-TB treatment medication.