呕吐毒素的LD_(50)表明其急性毒性较T-2毒素、雪腐镰刀菌烯醇等其他单端孢霉烯族化合物弱,但它可引起猪拒食、呕吐等。在啮齿动物的致畸和繁殖实验中,影响大鼠的体重增长,小鼠吸收胎增多、骨胳形成不良和仔鼠出 LD50 of DON is indicative of its acute toxicity compared with other trichothecenes such as T-2 toxins, snow rot Fusarium enolase, but it can cause pigs to refuse food, vomit and so on. In rodent teratogenic and reproductive experiments, effects on body weight gain, increased abortion in mice, poor skeletal formation, and offspring