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目的：研究ＴＭＵ（ＴｉａｎｊｉｎＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ）小黑鼠对６０Ｃｏ射线的敏感性。方法：将２４只ＴＭＵ小黑鼠随机分成３个剂量组（１０００Ｒｄ，８００Ｒｄ，６００Ｒｄ），并在８００Ｒｄ组设近交系ＴＡ２小鼠和远交系昆明种小鼠两个对照组，每组８只，雌雄各半，分别进行全身一次性６０Ｃｏ照射。以３０ｄ为限，观察动物存活情况。结果：１０００Ｒｄ组，ＴＭＵ小黑鼠平均存活６７５ｄ，８００Ｒｄ组，ＴＭＵ小黑鼠、ＴＡ２雄性小鼠、ＴＡ２雌性小鼠以及昆明种小鼠平均存活时间分别为６７５ｄ、９００ｄ、３０ｄ以上及１０６３ｄ；６００Ｒｄ组，ＴＭＵ小黑鼠平均存活３０ｄ以上。结论：ＴＭＵ小黑鼠对６０Ｃｏ射线的放射敏感性明显高于远交系昆明种小鼠，而与近交系ＴＡ２雄性小鼠相比较，则无明显差异。
Objective: To study the sensitivity of TMU (Tianjin Medical University) mice to 60Co radiation. Methods: Twenty-four TMU mice were randomly divided into three dose groups (1000Rd, 800Rd and 600Rd). In 800Rd group, two inbred TA2 mice and outbred Kunming mice were divided into two groups Only, male and female, respectively, a one-time whole body 60Co irradiation. To 30d limit, observe the survival of animals. Results: The average survival time of 1000Rd and TMU mice was 675 days. The average survival time of 800Rd, TMU mice, TA2 mice, TA2 mice and Kunming mice were 675 days and 900 days respectively, 30d and 1063d; 600Rd group, TMU mice survived more than 30d. Conclusion: The radiosensitivity of TMU mice to 60Co radiation is significantly higher than that of inbred Kunming mice, but there is no significant difference between TAU mice and TA2 male mice.