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上颌窦炎的致病菌对传统的抗生素多耐药,常见的葡萄球菌尤著,故应致力于选用能提高抗生素效价的抗菌制剂,如蜜蜂胶即其中之一。作者以此作了试管试验及临床观察。从上颌窦冲洗液中选出金黄色葡萄球菌20株及表皮葡萄球菌10株,与蜜蜂胶及青霉素、链霉素等5种抗生素在试管内作了单独及联合应用的试验。最低抑菌浓度平均值分析表明,蜜蜂胶在轻度制菌剂量时即引起所观察的5种抗生素中的4种抗葡萄球菌效力增强;青、链霉素尤著,其最低抑菌浓度比单独应用时平均下降25～40倍,在抗药性葡萄球菌菌株更为明显。
Pathogens of maxillary sinusitis are more resistant to traditional antibiotics and staphylococci are more common. Therefore, antibacterial agents that increase the potency of antibiotics, such as beeswax, should be applied. The authors made a test tube test and clinical observation. 20 strains of Staphylococcus aureus and 10 strains of Staphylococcus epidermidis were selected from the maxillary sinus irrigating solution, and 5 kinds of antibiotics such as bee glue, penicillin and streptomycin were tested individually and in combination in vitro. Analysis of the mean minimum inhibitory concentration showed that the efficacy of the four kinds of anti-staphylococci in the five antibiotics observed was enhanced at the dosage of mild bacteriocin; the ratio of cyanobacteria to streptomycin was the lowest, and the minimum inhibitory concentration ratio When applied alone, the average decline of 25 to 40 times, more resistant Staphylococcus aureus strains.